Sucralose #CAS56038-13-2
Sucralose #CAS56038-13-2
Sucralose is the only non-caloric sweetener made from sugar. It is in fact the latest non nutritive sweetener to have been approved by US FDA and other regulatory bodies and have hit the markets .
Sucralose is derived from sugar through a multi-step patented manufacturing process that selectively substitutes three atoms of chlorine for three hydroxyl groups on the sugar molecule. This change produces a sweetener that has no calories, yet is 600 times sweeter than sucrose, making it roughly twice as sweet as saccharin and four times as sweet as aspartame.
Application of Sucralose
High intensity sweetener manufactured by replacing three hydroxyl groups on the sucrose molecule with three chlorine atoms. The results are a sweetener of 0 cal that is not digested. It is 600 times as sweet as sugar with a similar flavor profile. It is heat stable, readily soluble, and maintains its stability at elevated temperatures. It has been approved for use in specific categories that include baked products, beverages, confectioneries, and certain desserts and toppings.
Sucralose (1,6-dichloro-1,6-dideoxy-p-fructofuranosyl-4-chloro-oc- D-galactopyra- noside) is a nonnutritive sweetener based on sucrose. It is selectively chlorinated and the glycoside link between the two rings is resistant to hydrolysis by acid or enzymes, so it is not metabolized. It has 400 to 800 times the sweetness of sucrose, is very soluble in water, and is stable in heat. It can be used in food products that are baked or fried.
Sucralose is produced by the selective chlorination of the sucrose molecule using a patented process by Tate and LyIe that replaces the three hydroxyl groups (OH) with three chlorine (Cl) atoms.
This modified sugar is minimally absorbed by the body and passes out unchanged. It was approved for use in foods and beverages in 1999 in the United States.
| Sucralose Chemical Properties |
| Melting point | 115-1018°C |
| Boiling point | 104-107 C |
| alpha | D +68.2° (c = 1.1 in ethanol) |
| density | 1.375 g/cm |
| vapor pressure | 0Pa at 25℃ |
| refractive index | 1.604 |
| storage temp. | 2-8°C |
| solubility | DMF: 30 mg/ml DMSO: 30 mg/mlPBS (pH 7.2): 1 mg/ml |
| form | Powder |
| pka | 12.52±0.70(Predicted) |
| color | White |
| PH | 6-8 (100g/l, H2O, 20°C) |
| Odor | wh. cryst. powd., odorless, sweet taste |
| Optical Rotation | [α]/D 86.0±2.0°, c = 1 in H2O |
| Water Solubility | Soluble in Water. |
| Merck | 14,8880 |
| BRN | 3654410 |
| Henry's Law Constant | 2.5×1013 mol/(m3Pa) at 25℃, HSDB (2015) |
| Stability: | Hygroscopic |
| Major Application | cleaning products cosmetics food and beverages personal care |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | 1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1 |
| InChIKey | BAQAVOSOZGMPRM-QBMZZYIRSA-N |
| SMILES | OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl |
| LogP | -0.51 at 20℃ |
| CAS DataBase Reference | 56038-13-2(CAS DataBase Reference) |
| EPA Substance Registry System | .alpha.-D-Galactopyranoside, 1,6-dichloro-1,6-dideoxy-.beta.-D-fructofuranosyl 4-chloro-4-deoxy- (56038-13-2) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39-24/25 |
| WGK Germany | 3 |
| RTECS | LW5440140 |
| HS Code | 2932 14 00 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 56038-13-2(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: > 10000 mg/kg |
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