Microcrystalline cellulose#CAS9004-34-6

CAS Number:9004-34-6

Chemical Formula:(C12H20O10)n

Synonyms:

  • AVICEL PH 101(R)

    HYCIL 102 MICROCRYSTALLINE CELLULOSE

  • HYCIL 101 MICROCRYSTALLINE CELLULOSE

    Appearance:White or almost white powder

  • MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)


Product Details

Microcrystalline cellulose#CAS9004-34-6

Odorless, white powdery fibers. Density 1.5 g cm-3. The biopolymer composing the cell wall of vegetable tissues. Prepared by treating cotton with an organic solvent to de-wax Cellulose microcrystalline and removing pectic acids by extration with a solution of sodium hydroxide. The principal fiber composing the cell wall of vegetable tissues (wood, cotton, flax, grass, etc.). Technical uses depend on the strength and flexibility of its fibers. Insoluble in water. Soluble with chemical degradation in sulfuric aicd, and in concentrated solutions of zinc chloride. Soluble in aqueous solutions of cupric ammonium hydroxide (Cu(NH3)4(OH)2).

Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles. It is commercially available in different particle sizes and moisture grades that have different properties and applications.

Application of Microcrystalline cellulose

ACCEL-101 is most widely used for direct compression tableting and wet granulation. ACCEL-102 has similar compression properties to ACCEL-101. However, it has larger particle size and therefore, may be of value in improving the flow if fine powders. ACCEL

cellulose is a thickener and an emulsifier. It is obtained from plants. cellulose (microcrystalline) is used as an emulsifier in cosmetic creams. It is the chief constituent of plant fiber.

Wood contains 50–70% cellulose; cotton and other textile fibers of plant origin contain 65–95%; rayon is prepared by dissolving natural cellulose and then precipitating it from solution, with some loss of crystallinity. Cellulose is made into cellophane film and is used to form fibers, resins, coatings and gums.

Microcrystalline Cellulose is a gum that is the nonfibrous form of cellulose, an alpha-cellulose. It is dispersible in water but not soluble, requiring considerable energy to disperse and hydrate. In this form it is used in dry applications such as tableting, capsules, and shredded cheese where it functions as a non-nutritive filler, binder, flow aid, and anticaking agent. By the addition of carboxymethylcellulose to the alpha-cellulose prior to drying, improved functional properties of hydration and dispersion are obtained. This product is designed for use in water dispersions, being insoluble in water but dispersing in water to form colloidal sols below 1% and white opaque gels above the 1% usage level. It is used as a heat shock stabilizer and bodying agent in frozen desserts, as an opacifier in low-fat dressings, as a foam stabilizer in whipped toppings, and as an emulsifier in dressings. Also termed cellulose gel.

Microcrystalline cellulose Chemical Properties
Melting point 76-78 °C(Solv: acetone (67-64-1); chloroform (67-66-3))
bulk density70-400kg/m3
density 1.5 g/cm3 (20℃)
refractive index n20/D 1.504
Fp 164 °C
storage temp. room temp
solubility Practically insoluble in water, in acetone, in anhydrous ethanol, in toluene, in dilute acids and in a 50 g/L solution of sodium hydroxide
form powder
color White or almost white
OdorOdorless
PH5-7.5 (100g/l, H2O, 20℃)(slurry)
biological sourcespruce
Optical Rotation-120 (Cuprammonium hydroxide solution)
Water Solubility insoluble
Merck 14,1965
Exposure limitsACGIH:TLV-TWA 10 mg/m3
OSHA:PEL-TWA 15 mg/m3 (total dust),5 mg/m3 (respirable fraction)
NIOSH:REL-TWA 10 mg/m3 (total dust),5 mg/m3 (respirable fraction)
Dielectric constant3.2(Ambient)
Stability:Stable. Combustible. Incompatible with strong oxidizing agents.
Cosmetics Ingredients FunctionsOPACIFYING
LIGHT STABILIZER
ABSORBENT
BULKING
EMULSION STABILISING
ABRASIVE
ANTICAKING
VISCOSITY CONTROLLING
Cosmetic Ingredient Review (CIR)Microcrystalline cellulose (9004-34-6)
InChI1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3,4,5,6,7,8,9,10-,11,12+/m1/s1
InChIKeyUFHFLCQGNIYNRP-UHFFFAOYSA-N
SMILESO1[C@H](C(C(C(C1CO)O)O)O)O[C@@H]2C(OC(C(C2O)O)O)CO
EPA Substance Registry SystemCellulose (9004-34-6)

Safety Information
Hazard Codes Xi
Risk Statements 37
Safety Statements 24/25
OEBB
OELTWA: 10 mg/m3 (total)
WGK Germany 3
RTECS FJ5950200
F 3
Autoignition Temperature232 °C
TSCA TSCA listed
HS Code 39129090
Storage Class11 - Combustible Solids
ToxicityLD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 2000 mg/kg

Fact Factory and Equipment Show

Magnesium oxideCAS:1309-48-4

Leave your messages

Related Products

x

Popular products

x