L-Threonine #CAS:72-19-5
CAS Number:72-19-5
Chemical Formula:C4H9NO3
Synonyms:
L-2-AMINO-3-HYDROXYBUTANOIC ACID
L-β-hydroxy-2-aminobutyric acid
L(-)-THREONINE;H-THR-OH-THREONINE
Appearance:White crystalline powder
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Product Details
L-Threonine #CAS:72-19-5
Isolation and identification of Threonine from the fiber protein hydrolyzate by W. C. Rose in 1935, has proved that it was the last essential amino acids. It is extremely important physiological role in animals, because it is the second or third limiting amino acids for livestock. Such as promoting growth, enhance immune function, etc. Balancing the dietary amino acids to make the ratio of close to the ideal protein, and reducing the protein content of livestock feed requirements. Lacking of threonine, may lead to reduce feed intake, growth retardation, decrease feed efficiency, and suppress immune function and other symptoms. In recent years, lysine, methionine synthesis product has widely used in feed, threonine become the limiting factor affected animal performance gradually. Further study of threonine could help to the livestock and poultry production effectively.Threonine cannot synthesize by animals, however, it is an essential amino acids for them to balance the composition of amino acids precisely to meet the need to animal growth, improve weight and lean meat, reduce the feed conversion. Threonine also can increase the value of feed raw materials of lower amino acid digestibility, and improve the production performance of low-energy feed. Besides, Threonine can reduce feed crude protein levels and improve feed nitrogen utilization, and reduce feed costs. So Threonine can be used for pigs, chickens, ducks and senior aquatic breeding and farming.
L-threonine is based on bio-engineering principles by using corn starch and other raw materials through submerged fermentation, refined and produced feed additives. L-threonine could adjust the balance of amino acid in feed, promote growth, improve meat quality and improve ncrease the value of feed raw materials of lower amino acid digestibility and produce the low protein feed, save protein resources, reduce the cost of feed ingredients, reduce the nitrogen content of manure and urine and decrease the concentration and release rate of animal building ammonia. L-threonine has used to add in piglet feed, pig feed, chicken feed, shrimp feed and eel feed widely.
Application of L-Threonine
Threonine is an important nutritional supplement which could fortify cereals, pastries, dairy products, restore the body as fatigue, and promote growth and development like tryptophan. Due to its structure contained threonine hydroxyl,which could held the water on human skin and combined with the oligosaccharide chains to protect cell membranes. Threonine plays an important role in the body, promoted phospholipid synthesis and fatty acid oxidation in the Medicine field as well.For biochemical research, the pharmaceutical amino acids could be a nutritional medicine to cure anemia primarily.
Amino acid as medicines is mainly used in amino acid infusion, comprehensive amino acid preparations and food nutrition fortifier. Such as the lack of threonine can cause loss of appetite, weight loss, fatty liver, testicular atrophy, anterior pituitary cells, dyeing changes and bone development. Adverse reactions Contraindications: When an adult infusion 22.5g, can cause fever, headaches and other adverse reactions.
Nutritional supplements. To meet the need of cereal protein, L-lysine is the first, another is L-threonine. Even though the content of L-threonine is high, the binding between peptide and threonine is difficult to hydrolysis, and not easy to absorb and digest.
It is also could be used in preparation of amino acid infusion and comprehensive amino acid preparations.
One of the essential amino acids in human body, it can be used to improve nutrition and physical fitness.
| L-Threonine Chemical Properties |
| Melting point | 256 °C (dec.) (lit.) |
| alpha | -28.4 º (c=6, H2O) |
| Boiling point | 222.38°C (rough estimate) |
| density | 1.3126 (rough estimate) |
| bulk density | 370kg/m3 |
| FEMA | 4710 | L-THREONINE |
| refractive index | -28 ° (C=6, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| pka | 2.09(at 25℃) |
| color | Yellow |
| PH | 5-6 (100g/l, H2O, 20℃) |
| Odor | ADM L-Threonine is a high quality product specifically designed for the feed industry. Produced from advanced technology, ADM L-Threonine is composed of 100% isomerically pure L-Threonine, which translates into 100% bioavailability for swine, poultry, and other animals.mild savory |
| Odor Type | savory |
| biological source | non-animal source |
| Optical Rotation | [α]20/D 28.5±0.5°, c = 5% in H2O |
| Water Solubility | 90 g/L (20 ºC) |
| Merck | 14,9380 |
| JECFA Number | 2119 |
| BRN | 1721646 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Major Application | cell analysis |
| Cosmetics Ingredients Functions | HAIR CONDITIONING ANTISTATIC HAIR WAVING OR STRAIGHTENING |
| InChI | 1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1 |
| InChIKey | AYFVYJQAPQTCCC-GBXIJSLDSA-N |
| SMILES | C[C@@H](O)[C@H](N)C(O)=O |
| LogP | -2.94 |
| CAS DataBase Reference | 72-19-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Threonine(72-19-5) |
| EPA Substance Registry System | L-Threonine (72-19-5) |
| CAS Number Unlabeled | 72-19-5 |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25-37/39-26 |
| WGK Germany | 3 |
| RTECS | XO8590000 |
| Hazard Note | Irritant |
| TSCA | TSCA listed |
| HS Code | 29225000 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 72-19-5(Hazardous Substances Data) |
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