L-Threonine #CAS72-19-5
CAS Number:72-19-5
Chemical Formula:C4H9NO3
Synonyms:
L-2-AMINO-3-HYDROXYBUTANOIC ACID
L(-)-THREONINE
(2S,3R)-L-Threonin
Appearance:White with thorhombic or crystalline powder. Odorless, taste sweet
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
L-Threonine #CAS72-19-5
It is stable under normal temperature and pressure. It is easily soluble in water, slightly soluble in ethanol, and insoluble in ether. Its aqueous solution shows neutral or weak acidity. It is not volatile under conventional storage conditions. It is hygroscopic and tends to absorb moisture when exposed to humid air. Under high temperature, strong acid or strong alkali conditions, the molecular structure will be destroyed and decomposition occurs. It can undergo Maillard reaction with reducing sugars at high temperature to form brown substances. It has good compatibility with most feed raw materials, mineral additives and vitamins. It is non-flammable and non-explosive, with low corrosiveness. It should be stored separately from strong oxidants.
Application of L-Threonine
1.Threonine is an important nutritional supplement which could fortify cereals, pastries, dairy products, restore the body as fatigue, and promote growth and development like tryptophan. Due to its structure contained threonine hydroxyl,which could held the water on human skin and combined with the oligosaccharide chains to protect cell membranes. Threonine plays an important role in the body, promoted phospholipid synthesis and fatty acid oxidation in the Medicine field as well.
2.For biochemical research, the pharmaceutical amino acids could be a nutritional medicine to cure anemia primarily.
3.Amino acid as medicines is mainly used in amino acid infusion, comprehensive amino acid preparations and food nutrition fortifier. Such as the lack of threonine can cause loss of appetite, weight loss, fatty liver, testicular atrophy, anterior pituitary cells, dyeing changes and bone development. Adverse reactions Contraindications: When an adult infusion 22.5g, can cause fever, headaches and other adverse reactions.
4.Nutritional supplements. To meet the need of cereal protein, L-lysine is the first, another is L-threonine. Even though the content of L-threonine is high, the binding between peptide and threonine is difficult to hydrolysis, and not easy to absorb and digest.
It is also could be used in preparation of amino acid infusion and comprehensive amino acid preparations.
5.One of the essential amino acids in human body, it can be used to improve nutrition and physical fitness.
amino acid, nutrient
L-Threonine is used to alleviate anxiety and mild depression. It is an important component of many proteins such as tooth enamel, collagen, and elastin. It is an important amino acid in the nervous system and plays a vital role in porphyrin and fat metabolism. It is useful in intestinal disorders and indigestion. It is also used as a prodrug to reliably elevate brain glycine levels.
| L-Threonine Chemical Properties |
| Melting point | 256 °C (dec.) (lit.) |
| alpha | -28.4 º (c=6, H2O) |
| Boiling point | 222.38°C (rough estimate) |
| density | 1.3126 (rough estimate) |
| bulk density | 370kg/m3 |
| FEMA | 4710 | L-THREONINE |
| refractive index | -28 ° (C=6, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| pka | 2.09(at 25℃) |
| color | Yellow |
| PH | 5-6 (100g/l, H2O, 20℃) |
| Odor | ADM L-Threonine is a high quality product specifically designed for the feed industry. Produced from advanced technology, ADM L-Threonine is composed of 100% isomerically pure L-Threonine, which translates into 100% bioavailability for swine, poultry, and other animals.mild savory |
| Odor Type | savory |
| biological source | non-animal source |
| Optical Rotation | [α]20/D 28.5±0.5°, c = 5% in H2O |
| Water Solubility | 90 g/L (20 ºC) |
| Merck | 14,9380 |
| JECFA Number | 2119 |
| BRN | 1721646 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| Major Application | cell analysis |
| Cosmetics Ingredients Functions | HAIR CONDITIONING ANTISTATIC HAIR WAVING OR STRAIGHTENING |
| InChI | 1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/m1/s1 |
| InChIKey | AYFVYJQAPQTCCC-GBXIJSLDSA-N |
| SMILES | C[C@@H](O)[C@H](N)C(O)=O |
| LogP | -2.94 |
| CAS DataBase Reference | 72-19-5(CAS DataBase Reference) |
| NIST Chemistry Reference | Threonine(72-19-5) |
| EPA Substance Registry System | L-Threonine (72-19-5) |
| CAS Number Unlabeled | 72-19-5 |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25-37/39-26 |
| WGK Germany | 3 |
| RTECS | XO8590000 |
| Hazard Note | Irritant |
| TSCA | TSCA listed |
| HS Code | 29225000 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 72-19-5(Hazardous Substances Data) |
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