Calcium phosphate #CAS:7758-87-4
CAS Number:7758-87-4
Chemical Formula:Ca3O8P2
Synonyms:
APATITE TTCP
MONOCLINIC
tricalcium phosphate for technical grade
Appearance:White
MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)
Calcium phosphate #CAS:7758-87-4
Calcium Phosphate is the calcium salt of phosphoric acid with widely used applications. It occur abundantly in nature in several forms and are the principal minerals for the production of phosphate fertilizers and for a range of phosphorus compounds. For example, the tribasic variety (precipitated calcium phosphate), Ca3(PO4)2, is the principal inorganic constituent of bone ash. The acid salt Ca(H2PO4)2, produced by treating mineral phosphates with sulfuric acid, is employed as a plant food and stabilizer for plastics. It is a natural constituent of mammals, and it is a component of bone replacement transplants in much higher amounts with no toxicological problems.
Calcium phosphates are the largest group of artificial bone graft substitutes. This is mainly due to their close resemblance to the mineral components of bone. This Product can be used as a countermeasure for exposure to strontium and radium radionuclides. Upon oral uptake, calcium phosphate competes for and blocks the absorption of radium (Ra-226) and strontium (Sr-90) in the gastrointestinal (GI) tract.
Application of Calcium phosphate
Calcium Phosphate is an anticaking agent and calcium source that is a white powder that is almost insoluble in water. It is used as an anticaking agent in table salt and dry vinegar. It is used as a source of calcium and phosphorus in cereals and desserts. It functions as a bleaching agent in flour and in lard, and prevents undesirable coloring and improves stability for frying. It is also termed tribasic calcium phosphate, tricalcium orthophosphate, calcium phosphate tribasic, and precipitated calcium phosphate.
Tricalcium phosphate has a wide range of applications across various fields, including the food industry, pharmaceuticals, the chemical industry, and materials science. Its primary areas of application are as follows:
Food Industry: It serves as an anti-caking agent, calcium fortifier, acidity regulator, flavoring agent, stabilizer, and moisture-retaining agent. In food processing, tricalcium phosphate helps prevent clumping, supplements calcium content, regulates pH balance, and supports bone health. It also functions as a pharmaceutical excipient and a material for bone repair.
Pharmaceuticals: Used as an antacid and a pharmaceutical excipient, tricalcium phosphate is valued in the pharmaceutical sector for its excellent biocompatibility and safety.
Chemical Industry: Tricalcium phosphate can be used in the production of ceramics and glass, or as a defluorinating agent in wastewater treatment.
Materials Science: In the field of construction materials, it is used as an additive for cement, helping to enhance both the strength and durability of the cement.
While tricalcium phosphate has a very broad scope of application, its effectiveness depends significantly on the specific context and method of use. In the food and pharmaceutical sectors, it is essential to adhere to national standards and carefully control dosage to ensure both safety and efficacy.
| Calcium phosphate Chemical Properties |
| Melting point | 1,670 °C (3,040 °F; 1,940 K) |
| density | 3.14 g/cm3 |
| refractive index | 1.63 |
| FEMA | 3081 | TRICALCIUM PHOSPHATE |
| Fp | Non-flammable |
| storage temp. | room temp |
| solubility | Practically insoluble in water. It dissolves in dilute hydrochloric acid and in dilute nitric acid. |
| form | amorphous powder |
| color | White |
| PH | 6-8 (50g/l, H2O, 20°C) suspension |
| Odor | Odorless |
| Water Solubility | 0.1 g/L (25 ºC) |
| Specific Heat Capacity | Cp(crystal): 0.73 J/(g·K), at 25℃ |
| Merck | 13,1699 |
| Solubility Product Constant (Ksp) | pKsp: 28.68 |
| Cosmetics Ingredients Functions | ORAL CARE ABRASIVE ANTICAKING FRAGRANCE OPACIFYING |
| Cosmetic Ingredient Review (CIR) | Calcium phosphate (7758-87-4) |
| InChI | 1S/3Ca.2H3O4P/c;;;2*1-5(2,3)4/h;;;2*(H3,1,2,3,4)/q3*+2;;/p-6 |
| InChIKey | QORWJWZARLRLPR-UHFFFAOYSA-H |
| SMILES | [Ca+2].[Ca+2].[Ca+2].[P](=O)([O-])([O-])[O-].[P](=O)([O-])([O-])[O-] |
| LogP | -2.15 |
| CAS DataBase Reference | 7758-87-4(CAS DataBase Reference) |
| EPA Substance Registry System | Tricalcium phosphate (7758-87-4) |
| Safety Information |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36-24/25-22 |
| WGK Germany | 3 |
| TSCA | TSCA listed |
| HS Code | 2835 26 00 |
| Storage Class | 11 - Combustible Solids |
| Hazardous Substances Data | 7758-87-4(Hazardous Substances Data) |
| Toxicity | LD50 orally in Rabbit: > 5000 mg/kg LD50 dermal Rabbit > 2000 mg/kg |
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